Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH
- Achterstrasse 30
- D-28359 Bremen
- Tel: +49 (0)421 218-56750
- Fax: +49 (0)421 218-56941
Institute director
Prof. Dr. Iris Pigeot
GErman POpulation Based LOng Term follow-up of ADHD
Description
- The attention-deficit/hyperactivity disorder (ADHD) in children and adolescents in Germany will be investigated in a pilot study consisting of 3 parts.
Part 1 consists of a database pilot-cohort study of approximately 90,000 children with an incident diagnosis of ADHD and controls without ADHD matched by age, sex and place of residence. Several health related outcomes will be investigated in children with ADHD compared to children without ADHD. The long term course of ADHD will be investigated in relation to the treatment administered. Predictors of the course of the disease will be identified.
Part 2 consists of a case-crossover study which will investigate the influence of drug therapy on the known increased risk of injuries in children with ADHD .
Part 3 consists of a feasibility study for a field part of the cohort-study which will investigate the feasibility of recruitment of study participants and the research tools.The negative and positive predictive value of diagnoses in the database will be determined by using neuropsychological examinations as gold standard. More than 600 children will be included in this part.
Funding period
- Begin: January 2009
End: September 2012
Sponsor
- Federal Ministry of Education and Research
Selected project-related publications
Articles with peer-review
- Lindemann, Christina; Langner, Ingo; Kraut, Angela; Banaschewski, Tobias; Schad-Hansjosten, Tanja; Petermann, Ulrike; Petermann, Franz; Schreyer-Mehlhop, Ina; Garbe, Edeltraut; Mikolajczyk, Rafael (2012). Age-specific prevalence, incidence of new diagnoses and drug treatment of attention-deficit / hyperactivity disorder in Germany. Journal of Child and Adolescent Psychopharmacology, 22 (4):307 - 314. http://dx.doi.org/10.1089/cap.2011.0064.
Presentations at scientific meetings/conferences
- Kraut, Angela; Langner, Ingo; Mikolajczyk, Rafael; Lindemann, Christina; Garbe, Edeltraut (2011). Comorbidities in methylphenidate users compared to nonusers in Germany. "Biometrie, Epidemiologie und Informatik - Gemeinsam forschen für Gesundheit". 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) und 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), 26.-29. September 2011, Mainz
- Langner, Ingo; Jobski, Kathrin; Mikolajczyk, Rafael; Kraut, Angela; Garbe, Edeltraut (2011). Methylphenidate and atomoxetine treatment of ADHD in children and youths in Germany. "Biometrie, Epidemiologie und Informatik - Gemeinsam forschen für Gesundheit". 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) und 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), 26.-29. September 2011, Mainz
- Lindemann, Christina; Kraut, Angela; Mikolajczyk, Rafael; Garbe, Edeltraut (2010). Methylphenidate treatment in Germany - Are co-morbidities taken into account? 26th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 19.-22. August 2010, Brighton, England
- Langner, Ingo; Lindemann, Christina; Kraut, Angela; Mikolajczyk, Rafael; Garbe, Edeltraut (2010). Incidence and prevalence of ADHD diagnoses in children and adolescents in Germany in 2005: A database study. Kongress "Individualisierte Prävention und Epidemiologie: Die moderne Medizin". Gemeinsame Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi), der Deutschen Gesellschaft für Sozialmedizin und Prävention (DGSMP) und der European Union of Medicine in Assurance and Social Security (EUMASS), 21.-25. September 2010, Berlin
Posters at scientific meetings/conferences
- Lindemann, Christina; Langner, Ingo; Kraut, Angela; Mikolajczyk, Rafael; Garbe, Edeltraut (2012). Regionale Unterschiede in der Häufigkeit der ADHS-Diagnosen in Deutschland. Methodenworkshop der Arbeitsgruppe Erhebung und Nutzung von Sekundärdaten (AGENS) der Deutschen Gesellschaft für Sozialmedizin und Prävention (DGSMP) und der Deutschen Gesellschaft für Epidemiologie (DGEpi), 22.-23. März 2012, Bremen
- Garbe, Edeltraut; Mikolajczyk, Rafael; Kraut, Angela; Langner, Ingo (2011). Drug treatment of ADHD in children and youths in Germany. 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 14.-17. August 2011, Chicago, USA. (Abstract publiziert in: Pharmacoepidemiology & Drug Safety. 2011;20(Suppl.1):132)
